Scott Disick
The Kardashian-Jenner family has been at the center of many weight loss rumors, and Scott Disick is part of that. In recent years, he’s lost a significant amount of weight, with plastic surgeons saying that the popular weight loss drug can lead to a “much thinner and skeletonized” look. In 2024, the Daily Mail revealed that Scott was reaching out to a nutritionist for health assistance, and he did confirm that he had used the GLP-1 medication Mounjaro, even joking about the experience in an ad for milk.

Kathy Bates
This talented, award-winning actress has always had a fuller figure, but after she was diagnosed with cancer multiple times as well as diabetes, she went on a healthy journey, shedding 100 pounds. Alongside her health journey was some alleged Ozempic usage, which many people suspected due to the rapid weight loss. However, on people speculating about her use of the drug, she told Ozempic, “People say, ‘Well, it was the Ozempic.’ It was the Ozempic! It took me years to do this. I got this diagnosis about diabetes—my father died of it; his mother died of it; one of my sisters is in peril. When they said ‘diabetes,’ I figured out what to do slowly, over the years, to lose the weight.”
Oprah Winfrey
This media mogul and daytime television icon has inspired people for decades, and through that time, her weight has fluctuated quite a bit, generating press and public comments that are not so kind. In a 2023 panel, she said, “My highest weight was 237 pounds. I don’t know if there is another public person whose weight struggle has been exploited as much as mine over the years.” Today, she’s undergone a full transformation with the help of a GLP-1 weight-loss medication, which she proudly champions “as a tool to help you manage the messages that are being sent to your brain about overeating.”
Ryan Seacrest
While many of the celebrities under fire for “Ozempic cheekbones” or “Ozempic face” are women, there are several famous men who are getting just as much flak for using the drug or ones like it. Ryan Seacrest, who you know from shows like “American Idol” and other shows on E!, has an especially gaunt look that’s been well-recorded. Though aging has contributed to a change in appearance, his recent ultra-thin look sparked conversations about GLP-1 usage, with startling cheekbones popping out for a skeletal look. Rumors are also swirling about a possible medical condition or plastic surgery, given how drastic the changes are.


